This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Rabbit Anti-Mouse Autocrine Motility Factor Receptor (AMFR) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for mouse autocrine motility factor receptor. It is purified by protein A/G. It can be applied to WB, IHC, ICC and IP assays of mouse autocrine motility factor receptor.
Specifications
Target Information
Mouse autocrine motility factor receptor (AMFR) is a multi-functional transmembrane protein with conserved cytosolic and extracellular domains, a core regulator of intracellular protein trafficking and signaling. It features an N-terminal extracellular domain for ligand binding, a single transmembrane helix, and a C-terminal cytosolic region with E3 ubiquitin ligase activity. It localizes predominantly to the endoplasmic reticulum membrane of mouse fibroblasts, epithelial cells and immune cells, with negligible expression in terminally differentiated neuronal tissues. The protein mediates substrate ubiquitination and membrane protein turnover, with conserved structural motifs differentiating it from other E3 ligase-containing receptors.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.