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Rabbit Anti-Mouse ATPase Na+/K+ Transporting Alpha 1 Polypeptide (ATP1a1) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for mouse ATPase, Na+/K+ transporting alpha 1 polypeptide. It is purified by protein A/G. It can be applied to WB, IHC, ICC and IP assays of mouse ATPase, Na+/K+ transporting alpha 1 polypeptide.
Specifications
Target Information
Mouse ATPase, Na+/K+ transporting alpha 1 polypeptide (ATP1A1) is a 113 kDa type-II membrane protein whose ten transmembrane helices form the catalytic core that exchanges three Na+ for two K+ against electrochemical gradients using ATP hydrolysis. A solvent-exposed 14-aa "KVE" loop (aa 710-723) between transmembrane segments 7 and 8 folds into a β-hairpin unique among mouse P-type ATPases, presenting a conformational epitope preserved after membrane isolation and fixation. Affinity-purified antibodies targeting this loop trace native ATP1A1 in basolateral membranes of nephron tubules, choroid plexus, and cardiac sarcolemma, delivering crisp lateral rings and single-band clarity on immunoblots with no cross-reaction to alpha 2 or alpha 3 isoforms.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.