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Rabbit Anti-Mouse Apoptosis Signal Regulating Kinase 1 (ASK1) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for mouse apoptosis signal regulating kinase 1. It is purified by protein A. It can be applied to WB, IHC, ICC and IP assays of mouse apoptosis signal regulating kinase 1.
Specifications
Target Information
Mouse Apoptosis Signal-Regulating Kinase 1 (ASK1) is a stress-responsive MAP3K that triggers JNK/p38 cascades by sensing oxidative or inflammatory stimuli. Inactive under reducing conditions, it is unleashed when thioredoxin is oxidized, making ASK1 a sensitive gauge of intracellular redox balance. High-affinity antibodies detect both the 140 kDa full-length and activated phosphorylated forms without cross-reaction with other MAP3Ks, enabling clear analysis of stress-driven apoptosis, fibrosis and metabolic signaling in mouse tissues and primary cells.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.