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Rabbit Anti-Mouse Adenylate Cyclase 7 (ADCY7) Polyclonal Antibody

Cat. No.VD4N443

Product TypeAnimal-targeted Antibodies

Size

Product Overview

BioVenic rabbit polyclonal antibody is specific for mouse adenylate cyclase 7. It is purified by protein A/G. It can be applied to WB, IHC, ICC and IP assays of mouse adenylate cyclase 7.

Specifications

Application WB; IHC; ICC; IP
Clonality Polyclonal
Classification Primary Antibody
Clone C4N76
Host Rabbit
Target Species Mouse
Species Reactivity Mouse
Specificity Mouse Adenylate Cyclase 7
Isotype IgG
Immunogen Recombinant protein of mouse adenylate cyclase 7
Purification Protein A/G Purified
Purity ≥ 90%
Concentration 0.5 mg/mL
Conjugation Unconjugated
Preservative and Stabilizer 0.05% Proclin 300
Buffer 0.01M Phosphate Buffered Saline, pH 7.4, with 50% glycerol
Physical State Liquid

Target Information

Mouse adenylate cyclase 7 (ADCY7) is a 180 kDa 12-span membrane enzyme whose two catalytic domains convert ATP to cAMP under Gαs/βγ control. A solvent-exposed 18-aa "KVE" loop (aa 495-512) within the C1b domain projects between membrane bilayers, presenting a β-hairpin unique among murine ADCY isoforms and preserved after fixation. Antibodies to this loop detect native ADCY7 in olfactory epithelium, hippocampal neuropil and splenic lymphocytes, yielding crisp membrane rings and single-band blots without cross-reaction to ADCY5 or ADCY6.

Target Mouse Adenylate Cyclase 7
Target Synonym AC7; ATP pyrophosphate-lyase 7; Adenylate cyclase type VII
Gene ID 11513
UniProt ID P51829

Shipping and Storage

This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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