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Rabbit Anti-Dihydrotestosterone (DHT) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for dihydrotestosterone. It is purified by protein A/G. It can be applied to ELISA, CLIA/IHC-Fr and ICC assays of dihydrotestosterone.
Specifications
Target Information
Dihydrotestosterone (DHT) is a 5α-reduced androgen characterized by a saturated A-ring that confers three- to five-fold higher androgen-receptor affinity than testosterone. Formed peripherally from testosterone by steroid 5α-reductase isoenzymes, the 19-carbon steroid circulates at nanomolar concentrations, largely bound to sex hormone-binding globulin. Its planar structure and short side-chain render DHT resistant to aromatization, directing signaling exclusively through androgen receptors. Antibodies elicited against DHT-protein conjugates exhibit strong selectivity over testosterone, 5α-androstane-3α,17β-diol and related androstanes, enabling precise detection of the active androgen in serum, tissue and cellular extracts across rodent and human matrices.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.