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Rabbit Anti-Canine Kidney Injury Molecule 1 (Kim1) Polyclonal Antibody

Cat. No.VD3N102

Product TypeAnimal-targeted Antibodies

Size

Product Overview

BioVenic rabbit polyclonal antibody is specific for canine kidney injury molecule 1. It is purified by Protein A Purified . It can be applied to WB, IHC, ICC and IP assays of canine kidney injury molecule 1.

Specifications

Application WB; IHC; ICC; IP
Clonality Polyclonal
Classification Primary Antibody
Clone Y1N600
Host Rabbit
Target Species Canine
Species Reactivity Canine
Specificity Canine Kidney Injury Molecule 1
Isotype IgG
Immunogen Recombinant protein of canine kidney injury molecule 1
Purification Protein A Purified
Concentration 0.5 mg/mL
Conjugation Unconjugated
Preservative and Stabilizer 0.05% Proclin 300
Buffer 0.01M Phosphate Buffered Saline, pH 7.4, with 50% glycerol
Physical State Liquid

Target Information

Canine Kidney Injury Molecule 1 (KIM-1) is a type I transmembrane glycoprotein expressed on the apical surface of injured proximal tubular epithelial cells. It functions as a scavenger receptor, mediating the phagocytosis of apoptotic bodies and limiting inflammatory damage during renal repair. Up-regulated within hours of ischemic or toxic insult, KIM-1 is a sensitive, tissue-specific biomarker of acute kidney injury. As a key indicator of tubular damage and regeneration, it is an important target for studies of nephrotoxicity and renal disease in dogs.

Target Canine Kidney Injury Molecule 1
Target Synonym HAVCR1; TIM1; TIMD1; HAVCR; Hepatitis A Virus Cellular Receptor 1; T Cell Immunoglobulin and Mucin Domain-Containing Protein 1; T-cell immunoglobulin mucin receptor 1

Shipping and Storage

This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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