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Rabbit Anti-Canine Interleukin 17 (IL17) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for canine interleukin 17. It is affinity purified by protein A. It can be applied to WB, IHC, ICC and IP assays of canine interleukin 17.
Specifications
Target Information
Canine Interleukin17 (IL17) is a pro-inflammatory cytokine primarily produced by activated T cells. It plays a critical role in recruiting and activating neutrophils, monocytes, and endothelial cells. IL-17 stimulates the production of IL-6, prostaglandin E, and nitric oxide, and synergizes with other inflammatory cytokines to amplify local inflammation. It also mediates chemotaxis of neutrophils and monocytes to sites of inflammation. In dogs, IL-17 is associated with various inflammatory diseases and has been implicated in the pathogenesis of autoimmune conditions such as immune-mediated hemolytic anemia (IMHA). The IL-17 receptor complex, formed by IL-17RA and IL-17RC, is widely expressed and mediates the pro-inflammatory effects of IL-17.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 2 years). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.