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Rabbit Anti-Bovine Liver X Receptor Alpha (LXRa) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for bovine liver X receptor alpha. It is purified by protein A/G. It can be applied to WB, IHC, ICC and IP assays of bovine liver X receptor alpha.
Specifications
Target Information
Bovine liver X receptor alpha (LXRα) is a nuclear ligand-activated transcription factor of the nuclear receptor superfamily. It features a conserved N-terminal DNA-binding domain with zinc-finger motifs, a C-terminal ligand-binding domain and coactivator interaction sites critical for structural integrity. It localizes to cell nuclei, with tissue-specific expression in bovine liver, intestine and macrophages, with minimal levels in skeletal muscle and adipose tissues. The protein mediates target gene transcription and ligand-dependent signaling, with conserved motifs for DNA binding and dimerization. Bovine LXRα shares core functional domains with mammalian orthologs, and has distinct ligand specificity differentiating it from LXRβ.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.