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Rabbit Anti-Bovine Hemoglobin Alpha 1 (HBa1) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for bovine hemoglobin alpha 1. It is purified by protein A/G. It can be applied to WB, IHC, ICC and IP assays of bovine hemoglobin alpha 1.
Specifications
Target Information
Bovine hemoglobin alpha 1 is a 15 kDa globular protein whose eight helices cradle a central heme, reversibly binding oxygen via proximal His-F8 and distal His-E7 coordination. A solvent-exposed 12-aa "KVE" loop (aa 34-45) between helices C and E folds into a β-turn unique among bovine globin chains, presenting a conformational epitope preserved after oxygenation and fixation. Affinity-purified antibodies targeting this loop trace native HBA1 in erythrocyte cytosol, bone-marrow reticulocytes, and pulmonary capillaries, delivering crisp cytoplasmic staining and single-band clarity on immunoblots with no cross-reaction to hemoglobin beta or fetal globins.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.