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Rabbit Anti-Bovine Haptoglobin (Hpt) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for bovine haptoglobin. It is purified by protein A/G. It can be applied to WB, IHC, ICC and IP assays of bovine haptoglobin.
Specifications
Target Information
Bovine haptoglobin (HP) is a secreted acute-phase glycoprotein of the globin-binding family, a core mediator of hemoglobin clearance and inflammatory response regulation. It features two conserved α-subunits and two β-subunits linked by disulfide bonds, a hemoglobin-binding pocket in the β-subunit, and structural domains critical for ligand affinity and protein stability. It localizes to the plasma and extracellular fluids of bovine hepatic and circulatory systems, with negligible levels in non-vascular and resting tissues. The protein mediates hemoglobin-HP complex formation and macrophage uptake, with conserved motifs for binding to hemoglobin and immune receptors. Bovine HP shares core functional domains with mammalian orthologs, and has distinct binding specificity differentiating it from other acute-phase proteins.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.