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Rabbit Anti-Bovine Caspase 8 (CASP8) Polyclonal Antibody

Cat. No.VD2N861

Product TypeAnimal-targeted Antibodies

Size

Product Overview

BioVenic rabbit polyclonal antibody is specific for bovine caspase 8. It is purified by Protein A Purified . It can be applied to WB, IHC, ICC and IP assays of bovine caspase 8.

Specifications

Application WB; IHC; ICC; IP
Clonality Polyclonal
Classification Primary Antibody
Clone Y1N360
Host Rabbit
Target Species Bovine
Species Reactivity Bovine
Specificity Bovine Caspase 8
Isotype IgG
Immunogen Recombinant protein of bovine caspase 8
Purification Protein A Purified
Concentration 1 mg/mL
Conjugation Unconjugated
Preservative and Stabilizer 0.02% Sodium Azide
Buffer Phosphate Buffered Saline, pH 7.4, with 50% glycerol
Physical State Liquid

Target Information

Bovine Caspase 8 is a crucial enzyme involved in the initiation of apoptosis, the programmed cell death pathway. It is activated in response to extrinsic signals, such as those from death receptors, and cleaves downstream substrates to propagate the apoptotic cascade. Caspase 8 also plays a role in regulating cell survival and inflammatory responses through non-apoptotic functions. Its activity is essential for maintaining tissue homeostasis and eliminating damaged or infected cells. As a key executor of apoptosis, bovine Caspase 8 is an important target for understanding cell death mechanisms and developing therapeutic strategies related to cell turnover and disease.

Target Bovine Caspase 8
Target Synonym CAP4; FLICE; MACH; MCH5; Cysteinyl Aspartate Specific Proteinases 8; Apoptotic cysteine protease; FADD-homologous ICE/ced-3-like protease; MORT1-associated ced-3 homolog
Gene ID 507481
UniProt ID Q2LGB8

Shipping and Storage

This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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