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Porcine Indoxyl Sulfate (IS) ELISA Kit-Competitive
Product Overview
BioVenic Porcine Indoxyl Sulfate (IS) ELISA Kit-Competitive is designed for the quantitative determination of Porcine IS in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Competitive ELISA method. For research use only.
Specifications
Target Information
Porcine Indoxyl Sulfate is a major protein-bound uremic toxin synthesized in the liver from indole produced by intestinal flora. In porcine models of renal dysfunction, IS accumulates due to reduced clearance, acting as a potent pro-oxidant and pro-inflammatory mediator. It triggers cellular senescence and interstitial fibrosis by activating the Aryl Hydrocarbon Receptor (AhR). Researchers utilize this target to investigate the pathophysiology of chronic kidney disease, vascular calcification, and the efficacy of renal replacement therapies in swine.
Shipping and Storage
This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.