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Porcine 3-Hydroxy-3-Methylglutaryl-Coenzyme A Reductase (HMGCR) ELISA Kit-Sandwich

Cat. No.EK12F608

Product TypeAnimal Immunoassay Kits

Size

Product Overview

BioVenic Porcine 3-Hydroxy-3-Methylglutaryl-Coenzyme A Reductase (HMGCR) ELISA Kit-Sandwich is designed for the quantitative determination of Porcine 3-Hydroxy-3-Methylglutaryl-Coenzyme A Reductase (HMGCR) in serum, plasma, tissue homogenate, cell culture supernatant, cell extract, and other biological fluids using a Sandwich ELISA method. For research use only.

Specifications

Assay Type ELISA-Sandwich
Specificity The assay kit is specific for Porcine HMGCR.
Target Species Swine
Species Reactivity Swine
Reproducibility Intra-Assay: CV < 10%; Inter-Assay: CV < 10%
Assay Time Around 270 min
Sample Requirement Serum, plasma, tissue homogenate, cell culture supernatant, cell extract, and other biological fluids.

Target Information

HMG-CoA reductase (official symbol HMGCR) is the rate-controlling enzyme in the mevalonate pathway, which is responsible for producing cholesterol and other isoprenoids. 3-Hydroxy-3-Methylglutaryl-Coenzyme A Reductase is encoded by the HMGCR gene in pigs. HMGCR is located in the endoplasmic reticulum (ER) membrane. It is a key enzyme in the pathway leading to cholesterol production. HMGCR is negatively associated with PCV2 infection in vitro and in vivo.

Target/Biomarker Porcine HMGCR
Target Synonym 3-hydroxy-3-methylglutaryl-coenzyme A reductase; HMG-CoA reductase; HMGCR; HMGR; 1.1.1.34
Gene ID 100144446
UniProt ID Q1W675

Shipping and Storage

This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

References

  1. Ouyang, T. et al. Porcine HMGCR Inhibits Porcine Circovirus Type 2 Infection by Directly Interacting with the Viral Proteins. Viruses. 2019, 11.
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