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Porcine Cytochrome C Oxidase Subunit 4 Isoform 1, Mitochondrial (COX4I1) ELISA Kit-Sandwich

Cat. No.EK12F471

Product TypeAnimal Immunoassay Kits

Size

Product Overview

BioVenic Porcine Cytochrome C Oxidase Subunit 4 Isoform 1, Mitochondrial (COX4I1) ELISA Kit-Sandwich is designed for the quantitative determination of Porcine Cytochrome C Oxidase Subunit 4 Isoform 1, Mitochondrial (COX4I1) in serum, plasma, tissue homogenate, cell culture supernatant, cell extract, and other biological fluids using a Sandwich ELISA method. For research use only.

Specifications

Assay Type ELISA-Sandwich
Specificity The assay kit is specific for Porcine COX4I1.
Target Species Swine
Species Reactivity Swine
Reproducibility Intra-Assay: CV < 10%; Inter-Assay: CV < 10%
Assay Time Around 270 min
Sample Requirement Serum, plasma, tissue homogenate, cell culture supernatant, cell extract, and other biological fluids.

Target Information

Cytochrome C Oxidase Subunit 4 Isoform 1, Mitochondrial is encoded by the COX4I1 gene in pigs. COX4I1 is a nuclear-encoded isoform of cytochrome c oxidase (COX) subunit 4. Cytochrome c oxidase (complex IV) is a multi-subunit enzyme complex that couples the transfer of electrons from cytochrome c to molecular oxygen and contributes to a proton electrochemical gradient across the inner mitochondrial membrane, acting as the terminal enzyme of the mitochondrial respiratory chain. Impairment of the cytochrome c oxidase, or complex IV, results in reactive oxygen intermediates promoting oxidative stress.

Target/Biomarker Porcine COX4I1
Target Synonym Cytochrome c oxidase subunit 4 isoform 1; mitochondrial; Cytochrome c oxidase polypeptide IV; Cytochrome c oxidase subunit IV isoform 1; COX IV-1; COX4I1; COX4
Gene ID 100624067
UniProt ID Q95283

Shipping and Storage

This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

References

  1. Holvoet, P. et al. Low Cytochrome Oxidase 1 Links Mitochondrial Dysfunction to Atherosclerosis in Mice and Pigs. PloS one. 2017, 12: e0170307.
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