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Porcine Caspase-1 (CASP1) ELISA Kit-Sandwich

Cat. No.EK12F419

Product TypeAnimal Immunoassay Kits

Size

Product Overview

BioVenic Porcine Caspase-1 (CASP1) ELISA Kit-Sandwich is designed for the quantitative determination of Porcine Caspase-1 (CASP1) in serum, plasma, tissue homogenate, cell culture supernatant, cell extract, and other biological fluids using a Sandwich ELISA method. For research use only.

Specifications

Assay Type ELISA-Sandwich
Specificity The assay kit is specific for Porcine CASP1.
Target Species Swine
Species Reactivity Swine
Reproducibility Intra-Assay: CV < 10%; Inter-Assay: CV < 10%
Assay Time Around 270 min
Sample Requirement Serum, plasma, tissue homogenate, cell culture supernatant, cell extract, and other biological fluids.

Target Information

Caspase-1, also known as interleukin-1β converting enzyme (ICE), is an evolutionarily conserved enzyme that proteolytically cleaves other proteins. Caspase-1 is encoded by the CASP1 gene in pigs. It is an enzyme that proteolytically cleaves other proteins, such as the precursors of the inflammatory cytokines IL1B and IL18 and the pyroptosis inducer gasdermin D, into active mature peptides. Research has shown that porcine GSDMD can be cleaved by pcaspase-1.

Target/Biomarker Porcine CASP1
Target Synonym Caspase-1; CASP-1; Interleukin-1 beta convertase; IL-1BC; Interleukin-1 beta-converting enzyme; ICE; IL-1 beta-converting enzyme; p45; CASP1; IL1BC; 3.4.22.36
Gene ID 397319
UniProt ID Q9N2I1

Shipping and Storage

This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

References

  1. Song, Y. et al. Porcine Gasdermin D Is a Substrate of Caspase-1 and an Executioner of Pyroptosis. Frontiers in immunology. 2022, 13.
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