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Mouse Zinc Finger Homeobox Protein 1B (ZFHX1B) ELISA Kit-Sandwich

Name: Mouse Zinc Finger Homeobox Protein 1B (ZFHX1B) ELISA Kit-Sandwich
SKU: EK6F290
Rating: 5 (1 reviews)

Cat. No.EK6F290

Product TypeAnimal Immunoassay Kits

Size

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Product Overview

BioVenic Mouse Zinc Finger Homeobox Protein 1B (ZFHX1B) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse ZFHX1B in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.

Specifications

Assay Type ELISA-Sandwich

Specificity The assay kit is specific for Mouse Zinc Finger Homeobox Protein 1B (ZFHX1B).

Target Species Mouse

Species Reactivity Mouse

Detection Range 0.17-10 ng/mL

Reproducibility Intra-Assay: CV < 10%; Inter-Assay: CV < 12%

Assay Time Around 90 min

Sample Requirement Serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids.

Target Information

Zinc Finger Homeobox Protein 1B, also known as SIP1 or ZFHX1B, is a transcriptional inhibitor that binds to the DNA sequence 5'-CACCT-3' in various promoters, repressing the transcription of E-cadherin and the expression of MEOX2. ZEB2 is crucial for the development of the mouse brain and spinal cord, as it regulates the migration and differentiation of cortical neurons, particularly in forming cortical granule cells and interneurons. Additionally, ZEB2 is involved in regulating midbrain dopamine axon growth and targeted projections; its absence leads to excessive innervation of striatal neurons.

Target/Biomarker Mouse ZFHX1B

Target Synonym ZEB2; SIP1; SIP-1; SMADIP1; SIP1; Zinc Finger E-Box Binding Homeobox 2; SMAD Interacting Protein 1

Gene ID 24136

UniProt ID Q9R0G7

Shipping and Storage

This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).

Documents

Datasheet

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

References

Birkhoff, Judith C et al. "ZEB2, the Mowat-Wilson Syndrome Transcription Factor: Confirmations, Novel Functions, and Continuing Surprises." Genes vol. 12,7 1037. 3 Jul. 2021.