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Mouse X-Ray Repair Cross Complementing 5 (XRCC5) ELISA Kit-Sandwich

Cat. No.EK6F436

Product TypeAnimal Immunoassay Kits

Size

Product Overview

BioVenic Mouse X-Ray Repair Cross Complementing 5 (XRCC5) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse XRCC5 in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.

Specifications

Assay Type ELISA-Sandwich
Specificity The assay kit is specific for Mouse X-Ray Repair Cross Complementing 5 (XRCC5).
Target Species Mouse
Species Reactivity Mouse
Detection Range 0.17-10 ng/mL
Reproducibility Intra-Assay: CV < 10%; Inter-Assay: CV < 12%
Assay Time Around 90 min
Sample Requirement Serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids.

Target Information

X-ray repair cross-complementing protein 5 is a single-stranded DNA-dependent, ATP-dependent helicase that plays a crucial role in DNA non-homologous end joining (NHEJ) by recruiting DNA-PK to DNA. It is essential for repairing double-strand breaks and V(D)J recombination. In mice, XRCC5 is vital for DNA repair, regulation of tumorigenesis, maintenance of immune function, and radiation resistance. Mice lacking XRCC5 exhibit severe immune deficiencies and heightened sensitivity to radiation, highlighting its importance not only in maintaining genomic stability during DNA repair but also in ensuring the normal functioning of immune cells.

Target/Biomarker Mouse XRCC5
Target Synonym KARP1; KU80; KUB2; Ku86; NFIV; TLAA; Lupus Ku Autoantigen Protein P80; Nuclear factor IV; 86 kDa of Ku antigen; CTC box-binding factor 85 kDa; Thyroid-lupus autoantigen
Gene ID 22596
UniProt ID P27641

Shipping and Storage

This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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