This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Mouse V-Ets Erythroblastosis Virus E26 Oncogene Homolog 1 (ETS1) ELISA Kit-Sandwich
Product Overview
BioVenic Mouse V-Ets Erythroblastosis Virus E26 Oncogene Homolog 1 (ETS1) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse ETS1 in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.
Specifications
Target Information
Protein C-ets-1 is a transcription factor that regulates the expression of cytokine and chemokine genes across various cellular contexts. It may influence the differentiation, survival, and proliferation of lymphoid cells. Mice lacking Ets1 (Ets1 KO) spontaneously develop autoimmune diseases and exhibit elevated levels of autoantibodies. Research indicates that Ets1-deficient CD4+ T cells are more prone to differentiate into Th17 cells, which secrete IL-17, a crucial factor in the development of autoimmune diseases. Furthermore, Ets1-deficient mice display significantly reduced numbers of NK cells and impaired functions, such as an inability to produce adequate IL-4.
Shipping and Storage
This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
References
- Battaglia, Michael et al. "Ets1 and IL17RA cooperate to regulate autoimmune responses and skin immunity to Staphylococcus aureus." Frontiers in immunology vol. 14 1208200. 23 Aug. 2023.