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Mouse Unconventional Myosin-Ib (MYO1B) ELISA Kit-Sandwich

Cat. No.EK6F950

Product TypeAnimal Immunoassay Kits

Size

Product Overview

BioVenic Mouse Unconventional Myosin-Ib (MYO1B) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse MYO1B in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.

Specifications

Assay Type ELISA-Sandwich
Specificity The assay kit is specific for Mouse Unconventional Myosin-Ib (MYO1B).
Target Species Mouse
Species Reactivity Mouse
Reproducibility Intra-Assay: CV < 10%; Inter-Assay: CV < 12%
Assay Time Around 90 min
Sample Requirement Serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids.

Target Information

Myo1b is a motor protein with diverse roles in cellular processes. It's thought to be involved in crucial neuronal functions such as cell migration, neurite outgrowth, and vesicular transport. In mice, Myo1b has been implicated in cellular senescence, vascular dysfunction, and tumor progression. Notably, it plays a significant role in endothelial cell (EC) senescence. Research indicates that Myo1b levels are elevated in the vascular endothelial cells of aged mice. This upregulation leads to inhibited autophagy and increased oxidative stress, which in turn promotes endothelial cell senescence and vascular dysfunction.

Target/Biomarker Mouse MYO1B
Target Synonym Unconventional myosin-Ib; Myo1b; MIH-L; Myosin I alpha (MMI-alpha; MMIa)
Gene ID 17912
UniProt ID P46735

Shipping and Storage

This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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