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Mouse Twist Transcription Factor (TWIST) ELISA Kit-Sandwich
Product Overview
BioVenic Mouse Twist Transcription Factor (TWIST) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse TWIST in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.
Specifications
Target Information
Twist-related protein 1 functions as a transcriptional regulator. It inhibits myogenesis by sequestering E proteins, blocking trans-activation by MEF2, and preventing MYOD1 from binding DNA through direct interaction, likely involving the basic domains of both proteins. In mice, Twist1 is widely expressed during early embryonic development, particularly in structures like the anterior mesoderm, primitive streaks, and neural crest-derived head mesoderm. It plays a crucial role in mesoderm formation and differentiation by regulating signaling pathways such as FGF, BMP, and TGFβ, thereby influencing the development of various mesoderm-derived tissues. Additionally, Twist1 is involved in the formation of heart valves and atrioventricular tubes.
Shipping and Storage
This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
References
- Vrljicak, Pavle et al. "Twist1 transcriptional targets in the developing atrio-ventricular canal of the mouse." PloS one vol. 7,7 (2012): e40815.