Mouse Tumor Necrosis Factor Alpha Induced Protein 2 (TNFaIP2) ELISA Kit-Sandwich

Tumor necrosis factor alpha-induced protein 2 (TNFAIP2) may serve as a mediator of inflammation and angiogenesis. Induced by tumor necrosis factor α (TNF-α), TNFAIP2 is a crucial target of the NF-κB signaling pathway and plays a significant role in inflammatory responses. It enhances immune responses by regulating cytokine secretion and facilitating T cell transendothelial migration. Additionally, TNFAIP2 is involved in the retinoic acid (RA) signaling pathway, further influencing cellular gene expression. In metabolic regulation, TNFAIP2 impacts stem cell differentiation and tissue homeostasis through exoc3-driven lipid metabolism. For example, embryonic stem cells from TNFAIP2 knockout mice fail to differentiate effectively into induced pluripotent stem cells (iPSCs), highlighting TNFAIP2's vital role in maintaining stem cell differentiation and tissue homeostasis.