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Mouse Tropomodulin 3 (TMOD3) ELISA Kit-Sandwich
Product Overview
BioVenic Mouse Tropomodulin 3 (TMOD3) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse TMOD3 in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.
Specifications
Target Information
Tropomodulin-3 inhibits both the elongation and depolymerization of actin filaments at their pointed ends. The Tmod/TM complex is integral to forming short actin protofilaments, which in turn define the geometry of the membrane skeleton. Tmod3 is crucial for the asymmetric division of mouse oocytes, as it preserves the integrity of the cytoplasmic actin network by binding to actin filaments. This support is essential for spindle migration and oocyte maturation. When Tmod3 is knocked down, it results in a weakened cytoplasmic actin network, inhibited spindle migration, and impaired asymmetric division.
Shipping and Storage
This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
References
- Jo, Yu-Jin et al. "Tropomodulin-3 is essential in asymmetric division during mouse oocyte maturation." Scientific reports vol. 6 29204. 4 Jul. 2016.