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Mouse Transforming Growth Factor Beta 2 (TGFb2) ELISA Kit-Competitive

Product Overview

BioVenic Mouse Transforming Growth Factor Beta 2 (TGFb2) ELISA Kit-Competitive is designed for the quantitative determination of Mouse TGFb2 in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Competitive ELISA method. For research use only.

Specifications

Assay Type ELISA-Competitive

Specificity The assay kit is specific for Mouse Transforming Growth Factor Beta 2 (TGFb2).

Target Species Mouse

Species Reactivity Mouse

Detection Range 31.25-2000 pg/mL

Reproducibility Intra-Assay: CV < 10%; Inter-Assay: CV < 12%

Assay Time Around 90 min

Sample Requirement Serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids.

Target Information

Transforming growth factor beta-2 (TGFβ2) is a versatile protein involved in regulating a variety of biological processes, including angiogenesis and cardiac development. In mice, TGFβ2 is crucial for embryonic development, particularly in forming the oral epithelium and the heart. Mice lacking TGFβ2 (Tgfb2−/−) exhibit significant developmental abnormalities, affecting areas such as the heart, craniofacial region, lungs, limbs, spine, eyes, inner ear, and urogenital system. In Tgfb2−/− embryos, heart defects are characterized by a double outlet right ventricle (DORV) and issues in myocardialization, both of which are linked to the disrupted apoptosis of neural crest cells.

Target/Biomarker Mouse TGFb2

Target Synonym TGF-B2; TGF-Beta2; G-TSF; LAP; Cetermin; Polyergin; Latency-associated peptide; BSC-1 cell growth inhibitor; Glioblastoma-derived T-cell suppressor factor

Gene ID 21808

UniProt ID P27090

Shipping and Storage

This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).

Documents

Datasheet

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

References

Fu, Chengyi et al. "Identification of New miRNA-mRNA Networks in the Development of Non-syndromic Cleft Lip With or Without Cleft Palate." Frontiers in cell and developmental biology vol. 9 631057. 1 Mar. 2021.