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Mouse Tissue Inhibitors of Metalloproteinase 4 (TIMP4) ELISA Kit-Sandwich
Product Overview
BioVenic Mouse Tissue Inhibitors of Metalloproteinase 4 (TIMP4) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse TIMP4 in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.
Specifications
Target Information
Metalloproteinase inhibitor 4 (TIMP-4) forms complexes with metalloproteinases, such as collagenases, and irreversibly deactivates them by binding to their catalytic zinc cofactor. In mice, TIMP-4 primarily functions through its broad inhibitory effect on MMPs and its regulatory role in cell migration, apoptosis, inflammation, fibrosis, and adipose tissue homeostasis. In an obese mouse model, TIMP-4 expression in adipose tissue is downregulated, possibly linked to adipose tissue remodeling and metabolic disorders. In a pulmonary fibrosis model, TIMP-4 expression is upregulated, and its ability to inhibit MMPs contributes to reducing lung damage.
Shipping and Storage
This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.