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Mouse Thyroid Stimulating Hormone Receptor Antibody (TRAb) ELISA Kit-Sandwich

Cat. No.EK5F63

Product TypeAnimal Immunoassay Kits

Size

Product Overview

BioVenic Mouse Thyroid Stimulating Hormone Receptor Antibody (TRAb) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse TRAb in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.

Specifications

Assay Type ELISA-Sandwich
Specificity The assay kit is specific for Mouse Thyroid Stimulating Hormone Receptor Antibody (TRAb).
Target Species Mouse
Species Reactivity Mouse
Detection Range 1.57-100 ng/mL
Reproducibility Intra-Assay: CV < 10%; Inter-Assay: CV < 12%
Assay Time Around 90 min
Sample Requirement Serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids.

Target Information

Thyroid stimulating hormone receptor antibodies (TSHR Ab), also known as TRAb, can have both stimulatory and blocking effects on the thyroid gland. These antibodies, which stimulate the thyrotropin receptor (TSHR), are the underlying cause of Graves' hyperthyroidism and are unique to humans. In mice, TSHR antibodies can be generated through immunization. Studies in mouse models show that TSHR antibodies play a key role in the occurrence and development of Graves disease. By studying the functions and mechanisms of these antibodies, the pathophysiological processes of Graves disease can be better understood and a theoretical basis for the development of new treatments.

Target/Biomarker Mouse TRAb
Target Synonym Thyroid Stimulating Hormone Receptor Antibody; TSHRAb;TSHR Ab; TRAb

Shipping and Storage

This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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