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Mouse Surfactant Associated Protein B (SPB) ELISA Kit-Sandwich
Product Overview
BioVenic Mouse Surfactant Associated Protein B (SPB) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse SPB in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.
Specifications
Target Information
Pulmonary surfactant-associated proteins enhance alveolar stability by reducing surface tension at the air-liquid interface within peripheral air spaces. SP-B, in particular, raises the collapse pressure of palmitic acid to nearly 70 millinewtons per meter. In neonatal mice, a deficiency in SP-B results in fatal respiratory distress syndrome (RDS), marked by alveolar collapse, drastically reduced lung compliance, and abnormal pulmonary surfactant. While SP-B deficiency in adult mice does not directly cause death, it greatly heightens susceptibility to oxygen-induced lung injury, evidenced by increased alveolar collapse, an intensified inflammatory response, and diminished lung function.
Shipping and Storage
This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.