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Mouse Sphingosine 1 Phosphate Receptor 5 (S1PR5) ELISA Kit-Sandwich
Product Overview
BioVenic Mouse Sphingosine 1 Phosphate Receptor 5 (S1PR5) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse S1PR5 in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.
Specifications
Target Information
Sphingosine 1-phosphate receptor 5 (S1PR5) serves as a receptor for the lysosphingolipid sphingosine 1-phosphate (S1P), a bioactive lysophospholipid that exerts a wide range of physiological effects on various cell types and tissues. S1PR5 is coupled to both the G(i/0)alpha and G12 subclass of heteromeric G-proteins. It is highly expressed in natural killer (NK) cells and patrolling monocytes (Ly6C− monocytes), playing a crucial role in their migration and localization. For instance, mice deficient in S1PR5 exhibit abnormal NK cell localization in lymph nodes, leading to decreased interferon-γ (IFN-γ) production. Moreover, S1PR5 is involved in the migration of patrolling monocytes from the bone marrow to peripheral tissues.
Shipping and Storage
This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.