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Mouse Solute Carrier Family 30, Member 3 (SLC30A3) ELISA Kit-Sandwich
Product Overview
BioVenic Mouse Solute Carrier Family 30, Member 3 (SLC30A3) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse SLC30A3 in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.
Specifications
Target Information
The proton-coupled zinc antiporter SLC30A3 likely facilitates the transport of zinc ions from the cytoplasm into synaptic vesicles, playing a role in maintaining zinc ion homeostasis in the brain. Known as ZnT3, this zinc transporter primarily ensures zinc homeostasis within synaptic vesicles. In mice, SLC30A3 is involved in various functions, including cognitive function, neuroprotection, metabolic regulation, and reproductive processes. Mice lacking ZnT3 (ZnT3 knockout) experience a significant decline in cognitive abilities, particularly in learning and memory. In the hippocampus, the absence of ZnT3 reduces synaptic zinc levels, adversely affecting synaptic plasticity and neuronal function.
Shipping and Storage
This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
References
- Hancock, Sara M et al. "Zinc Transporter-3 Knockout Mice Demonstrate Age-Dependent Alterations in the Metalloproteome." International journal of molecular sciences vol. 21,3 839. 28 Jan. 2020.