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Mouse Soluble Receptor for Advanced Glycation Endproducts (sRAGE) ELISA Kit-Sandwich
Product Overview
BioVenic Mouse Soluble Receptor for Advanced Glycation Endproducts (sRAGE) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse sRAGE in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.
Specifications
Target Information
sRAGE is the soluble form of the receptor that diminishes inflammation and oxidative stress by binding to advanced glycation end products (AGEs) and preventing their interaction with the cell surface receptor RAGE. Studies have demonstrated that sRAGE can inhibit apoptosis induced by hypoxia/reperfusion and reduce the incidence of apoptosis via the mitochondrial pathway. In mouse models, sRAGE has been shown to alleviate various chronic inflammatory diseases. Notably, sRAGE exhibits significant differential expression in mice with chronic colitis, possibly linked to its role in regulating inflammation. Furthermore, sRAGE has been found to enhance the function of bone marrow mesenchymal stem cells (MSCs) in diabetic environments, thereby promoting tissue repair and regeneration.
Shipping and Storage
This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.