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Mouse Soluble Receptor for Advanced Glycation Endproducts (sRAGE) ELISA Kit-Sandwich

Cat. No.EK6F738

Product TypeAnimal Immunoassay Kits

Size

Product Overview

BioVenic Mouse Soluble Receptor for Advanced Glycation Endproducts (sRAGE) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse sRAGE in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.

Specifications

Assay Type ELISA-Sandwich
Specificity The assay kit is specific for Mouse Soluble Receptor for Advanced Glycation Endproducts (sRAGE).
Target Species Mouse
Species Reactivity Mouse
Detection Range 2.6-165 pg/mL
Reproducibility Intra-Assay: CV < 10%; Inter-Assay: CV < 12%
Assay Time Around 90 min
Sample Requirement Serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids.

Target Information

sRAGE is the soluble form of the receptor that diminishes inflammation and oxidative stress by binding to advanced glycation end products (AGEs) and preventing their interaction with the cell surface receptor RAGE. Studies have demonstrated that sRAGE can inhibit apoptosis induced by hypoxia/reperfusion and reduce the incidence of apoptosis via the mitochondrial pathway. In mouse models, sRAGE has been shown to alleviate various chronic inflammatory diseases. Notably, sRAGE exhibits significant differential expression in mice with chronic colitis, possibly linked to its role in regulating inflammation. Furthermore, sRAGE has been found to enhance the function of bone marrow mesenchymal stem cells (MSCs) in diabetic environments, thereby promoting tissue repair and regeneration.

Target/Biomarker Mouse sRAGE
Target Synonym Soluble receptor for advanced glycation endproducts; sRAGE

Shipping and Storage

This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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