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Mouse Soluble Interleukin 6 Receptor (sIL-6R) ELISA Kit-Sandwich

Cat. No.EK5F701

Product TypeAnimal Immunoassay Kits

Size

Product Overview

BioVenic Mouse Soluble Interleukin 6 Receptor (sIL-6R) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse sIL-6R in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.

Specifications

Assay Type ELISA-Sandwich
Specificity The assay kit is specific for Mouse Soluble Interleukin 6 Receptor (sIL-6R).
Target Species Mouse
Species Reactivity Mouse
Detection Range 0.32-20 ng/mL
Reproducibility Intra-Assay: CV < 10%; Inter-Assay: CV < 12%
Assay Time Around 90 min
Sample Requirement Serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids.

Target Information

Interleukin-6 (IL-6) is a versatile cytokine that plays a significant role in various physiological and pathological processes, such as inflammation, immune regulation, neuroprotection, and within the cancer microenvironment. IL-6 initiates its effects by attaching to specific receptors, primarily the IL-6 receptor (IL-6R), which is its principal binding protein. This receptor exists in two forms: a soluble form (sIL-6R) and a transmembrane form. The sIL-6R can operate independently of the IL-6 signaling pathway, for instance, by suppressing IL-6's biological activity. In mice, the soluble IL-6 receptor is crucial for its biological functions, mainly by damping inflammatory responses and directing tissue repair through the regulation of the IL-6 signaling pathway.

Target/Biomarker Mouse sIL-6R
Target Synonym IL-6R;CD126; gp80; IL6R; IL-6R-1; IL-6R-Alpha; IL6RA; IL-6 receptor subunit alpha; Membrane glycoprotein 80; IL6R; Interleukin 6 Receptor

Shipping and Storage

This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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