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Mouse Sialic Acid Binding Ig Like Lectin 3 (SIGLEC3) ELISA Kit-Sandwich
Product Overview
BioVenic Mouse Sialic Acid Binding Ig Like Lectin 3 (SIGLEC3) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse SIGLEC3 in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.
Specifications
Target Information
The myeloid cell surface antigen CD33, also known as Sialic Acid Binding Ig Like Lectin 3 (SIGLEC3), is involved in facilitating cell-cell interactions and keeping immune cells in a resting state. It specifically binds sialic acid to the short O-linked glycans of certain mucins. In mice, SIGLEC3 plays a crucial role in regulating microglia function, contributing to the onset and progression of neurodegenerative diseases, and in cancer immunotherapy. In a mouse model of Alzheimer's disease (AD), an increase in SIGLEC3 expression is linked with the accumulation of amyloid β plaques, indicating its potential role in the disease's progression.
Shipping and Storage
This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.