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Mouse Serum/Glucocorticoid Regulated Kinase 3 (SGK3) ELISA Kit-Sandwich

Cat. No.EK6F790

Product TypeAnimal Immunoassay Kits

Size

Product Overview

BioVenic Mouse Serum/Glucocorticoid Regulated Kinase 3 (SGK3) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse SGK3 in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.

Specifications

Assay Type ELISA-Sandwich
Specificity The assay kit is specific for Mouse Serum/Glucocorticoid Regulated Kinase 3 (SGK3).
Target Species Mouse
Species Reactivity Mouse
Detection Range 0.17-10 ng/mL
Reproducibility Intra-Assay: CV < 10%; Inter-Assay: CV < 12%
Assay Time Around 90 min
Sample Requirement Serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids.

Target Information

Serine/threonine-protein kinase Sgk3 is an enzyme that regulates an array of ion channels, membrane transporters, and processes related to cell growth, proliferation, survival, and migration. It enhances cardiomyocyte proliferation and regeneration via the GSK-3β/β-catenin signaling pathway, thereby aiding in the recovery of cardiac function following injury, such as ischemia-reperfusion injury. Research indicates that overexpressing Sgk3 can significantly boost cell proliferation and advance cell cycle progression in the hearts of newborn mice, whereas inhibiting Sgk3 impedes this process. Additionally, Sgk3 offers protective effects in adult mice post-ischemia-reperfusion injury, promoting myocardial regeneration and aiding in the recovery of cardiac function.

Target/Biomarker Mouse SGK3
Target Synonym CISK; SGKL; Cytokine-independent survival kinase; Serum/glucocorticoid-regulated kinase-like; Serine/threonine-protein kinase Sgk3
Gene ID 170755
UniProt ID Q9ERE3

Shipping and Storage

This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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