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Mouse Serine/Threonine Kinase 11 (STK11) ELISA Kit-Sandwich
Product Overview
BioVenic Mouse Serine/Threonine Kinase 11 (STK11) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse STK11 in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.
Specifications
Target Information
Serine/threonine-protein kinase STK11 is a tumor suppressor kinase that regulates the activity of AMP-activated protein kinase (AMPK) family members. This regulation is crucial for various processes, including cell metabolism, cell polarity, apoptosis, and responses to DNA damage. Stk11-deficient mice display characteristics of high bone turnover, increased trabecular volume, and the formation of an irregular woven bone matrix, mirroring conditions seen in human diseases such as osteogenesis imperfecta and Jansen osteomalacia. In mouse models, dendritic cells (DCs) lacking Stk11 were unable to induce T cell activation, leading to significantly increased tumor growth.
Shipping and Storage
This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.