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Mouse Sequestosome 1 (SQSTM1) ELISA Kit-Sandwich

Cat. No.EK5F40

Product TypeAnimal Immunoassay Kits

Size

Product Overview

BioVenic Mouse Sequestosome 1 (SQSTM1) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse SQSTM1 in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.

Specifications

Assay Type ELISA-Sandwich
Specificity The assay kit is specific for Mouse Sequestosome 1 (SQSTM1).
Target Species Mouse
Species Reactivity Mouse
Detection Range 0.17-10 ng/mL
Reproducibility Intra-Assay: CV < 10%; Inter-Assay: CV < 12%
Assay Time Around 90 min
Sample Requirement Serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids.

Target Information

Sequestosome-1, encoded by the Sqstm1 gene in mice, is a molecular adapter essential for selective macroautophagy, known as aggrephagy. It functions as a bridge between polyubiquitinated proteins and autophagosomes. The protein facilitates the recruitment of ubiquitinated cargo proteins to autophagosomes through multiple domains, connecting proteins and organelles at different stages of the process. SQSTM1 has a wide range of functions in mice, involving many fields such as autophagy, cellular stress response, metabolic regulation, neurodegenerative diseases, cardiovascular diseases, and cancer.

Target/Biomarker Mouse SQSTM1
Target Synonym OSIL; PDB3; ZIP3; p62; p62B; p60; A170; Paget Disease Of Bone 3; Oxidative Stress Induced Like; EBI3-associated protein of 60 kDa; Ubiquitin-binding protein p62
Gene ID 18412
UniProt ID Q64337

Shipping and Storage

This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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