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Mouse Semaphorin 4D (SEMA4D) ELISA Kit-Sandwich
Product Overview
BioVenic Mouse Semaphorin 4D (SEMA4D) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse SEMA4D in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.
Specifications
Target Information
Semaphorin-4D (Sema4D) is a cell surface receptor for PLXNB1 and PLXNB2, playing a crucial role in cell-cell signaling and regulating the development of GABAergic synapses. Sema4D is extensively expressed in the central nervous system, particularly in the embryonic mouse brain, and is localized in neurons of adult mice. It is vital for guiding neuronal growth cones and notably promotes the rapid assembly of GABAergic synapses in the mouse hippocampus. Mice lacking Sema4D exhibit immune deficiencies but show no abnormalities in other organ functions. Additionally, these mice display a high bone mass phenotype, while their bone resorption process remains normal.
Shipping and Storage
This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
References
- Borggaard, Xenia G et al. "Spatial Organization of Osteoclastic Coupling Factors and Their Receptors at Human Bone Remodeling Sites." Frontiers in molecular biosciences vol. 9 896841. 14 Jun. 2022.