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Mouse Semaphorin 3C (SEMA3C) ELISA Kit-Sandwich
Product Overview
BioVenic Mouse Semaphorin 3C (SEMA3C) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse SEMA3C in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.
Specifications
Target Information
Semaphorin-3C interacts with plexin family members and is crucial for the regulation of developmental processes. It is essential for proper cardiovascular development during embryogenesis, acting as an attractant for growing axons and playing a significant role in axon growth and guidance. Sema3C is vital for the migration of cardiac neural crest cells (CNC) and the formation of the cardiac outflow tract (OFT). Research has demonstrated that Sema3C facilitates the migration and differentiation of CNC cells to the OFT by binding to NRP1, thereby ensuring the correct compartmentalization of the cardiac outflow tract. Mice lacking Sema3C exhibit defects in OFT development, including interrupted aortic arches and persistent pulmonary valves.
Shipping and Storage
This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.