This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Mouse Semaphorin 3B (SEMA3B) ELISA Kit-Sandwich
Product Overview
BioVenic Mouse Semaphorin 3B (SEMA3B) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse SEMA3B in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.
Specifications
Target Information
Semaphorin-3B restricts axonal growth by delivering localized signals that define areas off-limits to extending axons. This protein, primarily produced in response to 1,25-dihydroxyvitamin D3, is expressed by osteoblasts and is prevalent in mouse bones, particularly within osteoblasts and osteocytes. During the differentiation of osteoblasts, SEMA3B expression significantly rises, underscoring its crucial role in the physiological function of these cells. However, SEMA3B overexpression results in decreased bone density and abnormal trabecular architecture in mice. Additionally, in the context of neuronal synaptic plasticity, SEMA3B helps alleviate behavioral defects caused by chronic stress by upregulating proteins associated with synaptic plasticity.
Shipping and Storage
This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.