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Mouse Sclerostin Domain Containing Protein 1 (SOSTDC1) ELISA Kit-Sandwich

Cat. No.EK6F448

Product TypeAnimal Immunoassay Kits

Size

Product Overview

BioVenic Mouse Sclerostin Domain Containing Protein 1 (SOSTDC1) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse SOSTDC1 in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.

Specifications

Assay Type ELISA-Sandwich
Specificity The assay kit is specific for Mouse Sclerostin Domain Containing Protein 1 (SOSTDC1).
Target Species Mouse
Species Reactivity Mouse
Detection Range 15.7-1000 pg/mL
Reproducibility Intra-Assay: CV < 10%; Inter-Assay: CV < 12%
Assay Time Around 90 min
Sample Requirement Serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids.

Target Information

Sclerostin domain-containing protein 1 is potentially involved in initiating endometrial receptivity for implantation and sensitizing for the decidual cell reaction. It enhances Wnt signaling while inhibiting TGF-beta signaling. This protein directly antagonizes the activity of BMP2, BMP4, BMP6, and BMP7 in a dose-dependent manner. In mice, Sostdc1 serves various functions, including bone and tooth development, fracture healing, immune system regulation, and other tissue-specific roles. These functions are primarily achieved through its antagonistic action on the Wnt/β-catenin signaling pathway, though it also plays independent roles within specific tissues.

Target/Biomarker Mouse SOSTDC1
Target Synonym CDA019; USAG1; Ectodin; Ectodermal BMP inhibitor; Uterine sensitization-associated gene 1 protein
Gene ID 66042
UniProt ID Q9CQN4

Shipping and Storage

This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

References

  1. Tong, Xiaoyang et al. "Role of Sostdc1 in skeletal biology and cancer." Frontiers in physiology vol. 13 1029646. 21 Oct. 2022.
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