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Mouse S100 Calcium Binding Protein A7 (S100A7) ELISA Kit-Sandwich

Cat. No.EK5F928

Product TypeAnimal Immunoassay Kits

Size

Product Overview

BioVenic Mouse S100 Calcium Binding Protein A7 (S100A7) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse S100A7 in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.

Specifications

Assay Type ELISA-Sandwich
Specificity The assay kit is specific for Mouse S100 Calcium Binding Protein A7 (S100A7).
Target Species Mouse
Species Reactivity Mouse
Detection Range 0.24-15 ng/mL
Reproducibility Intra-Assay: CV < 10%; Inter-Assay: CV < 12%
Assay Time Around 90 min
Sample Requirement Serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids.

Target Information

S100A7, also known as psoriasin, is a calcium-binding protein prevalent in mammalian epidermal cells. In mice, S100A7 is involved in various functions, including tumor development, inflammatory response, wound healing, and antibacterial activity. Unlike its human counterpart, mouse S100A7 cannot function as a bacterial zinc source, limiting its use in certain bacterial infection studies due to the lack of a "zinc stealing" mechanism. S100A7 plays a dual role in cancer, with the ability to either promote or inhibit tumor development across various types. Additionally, S100A7 is important in inflammatory responses. Research indicates that it can enhance the mitochondrial function of epidermal cells and increase the secretion of IL-6 and IL-8, thereby contributing to the amplification of inflammatory signals.

Target/Biomarker Mouse S100A7
Target Synonym S100-A7; PSOR1; S100A7c; Psoriasin 1

Shipping and Storage

This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

References

  1. Sun, Wenyan et al. "Overexpression of S100A7 protects LPS-induced mitochondrial dysfunction and stimulates IL-6 and IL-8 in HaCaT cells." PloS one vol. 9,3 e92927. 26 Mar. 2014.
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