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Mouse Ribonucleotide Reductase M1 (RRM1) ELISA Kit-Sandwich
Product Overview
BioVenic Mouse Ribonucleotide Reductase M1 (RRM1) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse RRM1 in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.
Specifications
Target Information
The ribonucleoside-diphosphate reductase large subunit is crucial for providing the precursors necessary for DNA synthesis, catalyzing the conversion of ribonucleotides into deoxyribonucleotides. Research indicates that the expression level of Rrm1 is closely linked to the ability to repair DNA damage. For instance, in a mouse model of lung cancer, overexpression of Rrm1 significantly enhanced DNA damage repair and inhibited tumor formation. In mice, Rrm1 expression levels vary across different tissues; in skeletal muscle, its overexpression is primarily localized to that tissue. Additionally, high Rrm1 expression is associated with changes in mitochondrial DNA copy numbers, although this change is not significant.
Shipping and Storage
This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.