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Mouse Ribonuclease T2 (RNASET2) ELISA Kit-Sandwich
Product Overview
BioVenic Mouse Ribonuclease T2 (RNASET2) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse RNASET2 in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.
Specifications
Target Information
Ribonuclease T2-A is an enzyme vital for the innate immune response, as it identifies and degrades RNA from microbial pathogens for detection by TLR8. It specifically cleaves single-stranded RNA molecules between purine and uridine residues, contributing significantly to the production of catabolic uridine and the formation of purine-2',3'-cyclophosphate-terminated oligoribonucleotides. RNASET2 is key to several biological processes, including tumor suppression, immune regulation, and nervous system functionality. Under hypoxic conditions, RNASET2 can enhance its expression via the PI3K/AKT signaling pathway, thereby influencing the function of dendritic cells.
Shipping and Storage
This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
References
- Monaci, Sara et al. "Hypoxia Enhances the Expression of RNASET2 in Human Monocyte-Derived Dendritic Cells: Role of PI3K/AKT Pathway." International journal of molecular sciences vol. 22,14 7564. 15 Jul. 2021.