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Mouse Rhodopsin (RHO) ELISA Kit-Sandwich

Cat. No.EK6F349

Product TypeAnimal Immunoassay Kits

Size

Product Overview

BioVenic Mouse Rhodopsin (RHO) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse RHO in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.

Specifications

Assay Type ELISA-Sandwich
Specificity The assay kit is specific for Mouse Rhodopsin (RHO).
Target Species Mouse
Species Reactivity Mouse
Detection Range 0.17-10 ng/mL
Reproducibility Intra-Assay: CV < 10%; Inter-Assay: CV < 12%
Assay Time Around 90 min
Sample Requirement Serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids.

Target Information

Rhodopsin is a photoreceptor essential for image-forming vision at low light levels and is crucial for the viability of photoreceptor cells after birth. In mice, rhodopsin's function is intrinsically linked to its role in retinal rod photoreceptors. The expression level of rhodopsin directly influences the morphology and function of rod cell outer segments. In heterozygous mutant mice (Rho+/−), a 50% reduction in rhodopsin expression results in a 30-40% reduction in the length and a 20% reduction in the diameter of rod cell outer segments, leading to decreased density of the outer segment membrane disks.

Target/Biomarker Mouse RHO
Target Synonym OPN2; RP4; Opsin 2; Rod Pigment; Retinitis Pigmentosa 4; Visual Purple
Gene ID 212541
UniProt ID P15409

Shipping and Storage

This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

References

  1. Makino, Clint L et al. "Rhodopsin expression level affects rod outer segment morphology and photoresponse kinetics." PloS one vol. 7,5 (2012): e37832.
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