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Mouse Retinal Photoreceptor Cells-661W-GFP-Puro

Product Overview

661W mouse retinal photoreceptor cells are an immortalized cell line derived from transgenic mice, possessing characteristics of both retinal ganglion cells (RGCs) and photoreceptor cells. This cell line originated from transgenic mice expressing the SV40 T-antigen under the control of the human interphotoreceptor retinoid-binding protein promoter. It is used to study diseases such as inherited retinal degeneration (IRD), glaucoma, macular degeneration, retinitis pigmentosa (RP) caused by rhodopsin mutations, and retinal ciliopathies. Additionally, 661W cells can be used to investigate phototransduction and retinal function. The cells were transfected with lentivirus to carry the GFP gene.

Specifications

Cell Product Type Cell Line

Species Mouse

Cell Type Retinal Photoreceptor Cells

Source Eye

Growth Information Adherent; 37°C; 5%CO₂

Quality Control Mycoplasma (-); Bacteria (-); Yeast (-); Fungi (-)

Formulation and Cell Culture Medium DMEM-H with 10% FBS; 1% Penicillin-Streptomycin Solution; 0.4 μg/mL Puro

Physical State Frozen cells

Target Information

This cell line is a cell line stably expressing GFP.

Shipping and Storage

This product is shipped with dry ice. It's recommended to store the product with liquid nitrogen and never in a -20 °C or -80 °C refrigerator. Avoid repeated freezing and thawing of the product.

Documents

Datasheet

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.