Mouse Renin (REN) ELISA Kit-Sandwich

Renin in mice serves several critical roles, primarily in regulating blood pressure, maintaining kidney function, and potentially influencing brain barrier integrity and cognitive abilities. It is a pivotal enzyme in the renin-angiotensin system (RAS), where it controls blood pressure by cleaving angiotensinogen to form angiotensin I (AI). Research indicates that mice lacking renin experience notable hypotension, increased urine output, greater water consumption, and altered glomerular structure, underscoring renin's essential role in sustaining blood pressure and kidney health. Besides its role in blood pressure regulation, renin may impact other physiological processes. For instance, studies suggest that mice without renin show enhanced cognitive performance in behavioral assessments.