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Mouse Regenerating Islet Derived Protein 3 Beta (REG3b) ELISA Kit-Sandwich

Cat. No.EK6F505

Product TypeAnimal Immunoassay Kits

Size

Product Overview

BioVenic Mouse Regenerating Islet Derived Protein 3 Beta (REG3b) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse REG3b in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.

Specifications

Assay Type ELISA-Sandwich
Specificity The assay kit is specific for Mouse Regenerating Islet Derived Protein 3 Beta (REG3b).
Target Species Mouse
Species Reactivity Mouse
Detection Range 9.38-600 pg/mL
Reproducibility Intra-Assay: CV < 10%; Inter-Assay: CV < 12%
Assay Time Around 90 min
Sample Requirement Serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids.

Target Information

Regenerating islet-derived protein 3-beta is a bactericidal C-type lectin effective against various intestinal Gram-positive and Gram-negative bacteria, though it lacks activity against S. typhimurium. It may contribute to protection against S. enteritidis infection by preventing its translocation from the gut lumen into intestinal and extraintestinal tissues. In mouse models, Reg3β has been shown to alleviate symptoms of intestinal inflammation and colitis. In DSS-induced colitis, mice deficient in Reg3β exhibited more severe inflammatory responses, characterized by increased leukocyte infiltration and elevated IL-6 levels.

Target/Biomarker Mouse REG3b
Target Synonym PAP1; Pancreatitis-Associated Protein 1
Gene ID 18489
UniProt ID P35230

Shipping and Storage

This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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