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Mouse Pulmonary Artery Smooth Muscle Cells-Immortalized by SV40T Antigens

Cat. No.CC7F228

Product TypeAnimal Cells and Cell Lines

Product Overview

The pulmonary artery originates from the right ventricle and runs obliquely upwards and backwards in front of the aorta. Below the aortic arch, it divides into the left and right pulmonary arteries, which enter the lungs via the hilum. Although the pulmonary artery is an artery, it carries deoxygenated (venous) blood because it connects to the right ventricle, which pumps deoxygenated blood. The calcium channels expressed by these cells have ICAM-1 and VCAM-1 expressed on their surface, which participate in vascular wall inflammatory responses. In vitro cultured pulmonary artery smooth muscle cells appear spindle-shaped, star-shaped, or irregular. Mouse Pulmonary Artery Smooth Muscle Cells-Immortalized by SV40T Antigens were immortalized through lentiviral transfection carrying the SV40 gene (these cells acquire puromycin resistance after transfection).

Specifications

Cell Product Type Cell Line
Species Mouse
Cell Type Immortalized Cell Line
Source Pulmonary Artery
Growth Information Adherent; 37°C; 5%CO2
Quality Control Mycoplasma (-); Bacteria (-); Yeast (-); Fungi (-)
Physical State Frozen cells

Target Information

These cells are transformed and stably express the large T-antigen of the simian virus 40 (SV40T antigens) to immortalize the cells and extend their lifespan.

Target/Biomarker SV40T antigens
Target Synonym large T antigen [ Simian virus 40 ]
Gene ID 1489531

Shipping and Storage

This product is shipped with dry ice. It's recommended to store the product with liquid nitrogen and never in a -20 °C or -80 °C refrigerator. Avoid repeated freezing and thawing of the product.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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