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Mouse Protein Kinase B Alpha (PKBa) ELISA Kit-Sandwich
Product Overview
BioVenic Mouse Protein Kinase B Alpha (PKBa) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse PKBa in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.
Specifications
Target Information
RAC-alpha serine/threonine-protein kinase, commonly known as Akt1, is one of three closely related serine/threonine-protein kinases in the AKT kinase family, alongside AKT2 and AKT3, that regulate numerous processes, including metabolism, proliferation, cell survival, growth, and angiogenesis. Knockout mice lacking Akt1 displayed growth retardation and weight loss, underscoring the pivotal role of Akt1 in mouse growth and development. Additionally, Akt1-deficient mice exhibited significant bone development defects, such as reduced bone density, decreased trabecular thickness, and lower fracture resistance.
Shipping and Storage
This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
References
- Mukherjee, Aditi et al. "Distinct actions of akt1 on skeletal architecture and function." PloS one vol. 9,3 e93040. 24 Mar. 2014