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Mouse Protectin (CD59) ELISA Kit-Sandwich

Cat. No.EK5F811

Product TypeAnimal Immunoassay Kits

Size

Product Overview

BioVenic Mouse Protectin (CD59) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse CD59 in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.

Specifications

Assay Type ELISA-Sandwich
Specificity The assay kit is specific for Mouse Protectin (CD59).
Target Species Mouse
Species Reactivity Mouse
Detection Range 62.5-4000 pg/mL
Reproducibility Intra-Assay: CV < 10%; Inter-Assay: CV < 12%
Assay Time Around 90 min
Sample Requirement Serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids.

Target Information

CD59, also known as Protectin, is a glycoprotein that serves as a potent inhibitor of the complement membrane attack complex (MAC). It functions by binding to the C8 and/or C9 components of the assembling MAC, thus preventing the incorporation of multiple C9 copies necessary for the full formation of the osmolytic pore. In mice, CD59 is encoded by two genes: mCD59a and mCD59b. mCD59a is broadly expressed across various tissues and cell types, including endothelial cells, red blood cells, and platelets, acting as a key regulator of the terminal complement pathway. Meanwhile, mCD59b is predominantly expressed in testicular germ cells and mature sperm and may have additional physiological roles.

Target/Biomarker Mouse CD59
Target Synonym MIC11; MIN1; MIN2; MIN3; MSK21; MAC-IP; MACIF; MIRL; HRF20; Complement Regulatory Protein; 20 kDa homologous restriction factor; Membrane attack complex inhibition factor

Shipping and Storage

This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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