Mouse Prostaglandin Endoperoxide Synthase 2 (PTGS2) ELISA Kit-Sandwich

Prostaglandin G/H synthase 2 is an enzyme with dual cyclooxygenase and peroxidase activities, involved in the biosynthesis of prostanoids-a class of C20 oxylipins primarily derived from arachidonate-playing a significant role in the inflammatory response. In mice, Ptgs2 has diverse and vital functions, including regulating inflammation, reproductive processes, metabolic pathways, and cellular stress responses. In an acute lung injury model, Ptgs2 modulates the inflammatory response by promoting lipoxin production. Research indicates that the absence of Ptgs2 can result in various reproductive issues, such as ovulation failure, fertilization disorders, and embryo implantation failure. Additionally, Ptgs2 is crucial in lipid metabolism; for example, in mice with imbalanced intestinal microbiota, it participates in lipid metabolic pathways.