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Mouse Prion Protein (PRNP) ELISA Kit-Sandwich
Product Overview
BioVenic Mouse Prion Protein (PRNP) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse PRNP in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.
Specifications
Target Information
The major prion protein is believed to contribute to neuronal development and synaptic plasticity and might be essential for maintaining the neuronal myelin sheath. It may facilitate myelin homeostasis by acting as an agonist for the ADGRG6 receptor. Additionally, it could have a role in iron uptake and maintaining iron homeostasis. In mice, prion protein (PrP) is closely linked to various neurodegenerative diseases. Mutations or abnormal conformations of PrP, such as PrPSc, can cause neurodegenerative changes similar to human conditions like Creutzfeldt-Jakob disease, leading to spongiform encephalopathy, neuronal death, and gliosis.
Shipping and Storage
This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.